Bunyaviruses: general features

Elliott, R.M. (2008) Bunyaviruses: general features. In: Mahy, B.W.J. and Van Regenmortel, M.H.V. (eds.) Encyclopedia of Virology. Elsevier: Oxford, UK, pp. 390-399. ISBN 9780123744104 (doi:10.1016/B978-012374410-4.00785-8)

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Publisher's URL: http://dx.doi.org/10.1016/B978-012374410-4.00785-8

Abstract

The Bunyaviridae is one of the largest families of viruses, containing more than 300 named isolates. The viruses are characterized by a tripartite, single-stranded RNA genome that encode their gene products using a negative-sense or ambisense strategy. The family is classified into five genera: Orthobunyavirus, Hantavirus, Nairovirus, Phlebovirus, and Tospovirus. Most of these viruses (except hantaviruses) are transmitted by arthropod vectors, and many are associated with diseases in humans, domesticated animals, or plants. The interaction between virus and vector is discussed. The virion RNAs and proteins of viruses in different genera are schematically summarized and the bunyavirus replication cycle is described. Finally, the importance of reverse genetics to the study of these viruses is emphasized.

Item Type:Book Sections (Encyclopaedia entry)
Status:Published
Glasgow Author(s) Enlighten ID:Elliott, Professor Richard
Authors: Elliott, R.M.
College/School:College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation
Publisher:Elsevier
ISBN:9780123744104

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
656531Structural studies on human virusesFrazer RixonMedical Research Council (MRC)MC_UU_12014/6MVLS III - CENTRE FOR VIRUS RESEARCH
656321Genomics of human cytomegalovirusAndrew DavisonMedical Research Council (MRC)MC_UU_12014/3MVLS III - CENTRE FOR VIRUS RESEARCH