Solid-phase synthesis of peptidosulfonamide containing peptides derived from Leu-enkephalin

de Bont, D.B.A., Dijkstra, G.D.H., den Hartog, J.A.J. and Liskamp, R.M.J. (1996) Solid-phase synthesis of peptidosulfonamide containing peptides derived from Leu-enkephalin. Bioorganic and Medicinal Chemistry Letters, 6(24), pp. 3035-3040. (doi:10.1016/S0960-894X(96)00565-3)

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Abstract

Using Boc or Fmoc-protected β-substituted aminoethanesulfonyl chlorides (2-substituted taurylchlorides) the solid-phase synthesis of dipeptidosulfonamides as well as peptidosulfonamide containing peptides derived from Leu-enkephalin is described. The binding activity of the peptidosulfonamide YGGFL derivatives is reported.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Liskamp, Professor Robert
Authors: de Bont, D.B.A., Dijkstra, G.D.H., den Hartog, J.A.J., and Liskamp, R.M.J.
College/School:College of Science and Engineering > School of Chemistry
Journal Name:Bioorganic and Medicinal Chemistry Letters
ISSN:0960-894X
ISSN (Online):1464-3405

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