Approaches to the synthesis of ureapeptoid peptidomimetics

Kruijtzer, J.A.W., Lefeber, D.J. and Liskamp, R.M.J. (1997) Approaches to the synthesis of ureapeptoid peptidomimetics. Tetrahedron Letters, 38(30), pp. 5335-5338. (doi: 10.1016/S0040-4039(97)01166-0)

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Ureapeptoid peptidomimetics can be composed from Boc-protected N-substituted ethylenediamines. The best approach is to synthesize these from chloroacetonitrile followed by conversion to the corresponding crystalline p-nitrophenyl carbamates in order to prepare the ureapeptoids.

Item Type:Articles
Glasgow Author(s) Enlighten ID:Liskamp, Professor Robert
Authors: Kruijtzer, J.A.W., Lefeber, D.J., and Liskamp, R.M.J.
College/School:College of Science and Engineering > School of Chemistry
Journal Name:Tetrahedron Letters

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