Solution phase combinatorial chemistry using cyclotriveratrylene-based tripodal scaffolds

van Wageningen, A.M.A. and Liskamp, R.M.J. (1999) Solution phase combinatorial chemistry using cyclotriveratrylene-based tripodal scaffolds. Tetrahedron Letters, 40(52), pp. 9347-9351. (doi:10.1016/S0040-4039(99)01979-6)

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Abstract

A library consisting of 40 cyclotriveratrylene-based tripodal scaffold molecules was constructed by O-alkylation of the CTV-triol followed by coupling of one or two amino acids; apart from the wash steps in the work-up the reaction products did not require additional purification. Preliminary screening experiments revealed that a dansylated receptor molecule selectively bound N-acylated dipeptides.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Liskamp, Professor Robert
Authors: van Wageningen, A.M.A., and Liskamp, R.M.J.
College/School:College of Science and Engineering > School of Chemistry
Journal Name:Tetrahedron Letters
ISSN:0040-4039
ISSN (Online):1873-3581

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