Vrasidas, I., Kemmink, J., Liskamp, R.M.J. and Pieters, R. J. (2002) Synthesis and cholera toxin binding properties of a lactose-2-aminothiazoline conjugate. Organic Letters, 4(10), pp. 1807-1808. (doi: 10.1021/ol025909w)
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Abstract
During the search for improved monovalent ligands for cholera toxin (CT), a new lactose-2-aminothiazoline conjugate was discovered. In a fluorescence binding assay the compound was found to be one of the strongest relatively simple CT ligands to date with a Kd of 23 μM.
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Liskamp, Professor Robert |
Authors: | Vrasidas, I., Kemmink, J., Liskamp, R.M.J., and Pieters, R. J. |
College/School: | College of Science and Engineering > School of Chemistry |
Journal Name: | Organic Letters |
ISSN: | 1523-7060 |
ISSN (Online): | 1523-7052 |
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