High-yielding microwave-assisted synthesis of triazole-linked glycodendrimers by copper-catalyzed [3+2] cycloaddition

Joosten, J.A.F., Tholen, N.T.H., Ait El Maate, F., Brouwer, A.J., van Esse, G.W., Rijkers, D.T.S., Liskamp, R.M.J. and Pieters, R.J. (2005) High-yielding microwave-assisted synthesis of triazole-linked glycodendrimers by copper-catalyzed [3+2] cycloaddition. European Journal of Organic Chemistry, 2005(15), pp. 3182-3185. (doi: 10.1002/ejoc.200500216)

Abstract

A facile and high-yielding synthesis of multivalent 1,4-disubstituted 1,2,3-triazole-linked glycodendrimers is described. Azido carbohydrates are linked by a CuI-catalyzed [3+2] cycloaddition reaction to dendritic acetylenes using microwave irradiation.

• Item Type: Articles
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Liskamp, Professor Robert
• Authors: Joosten, J.A.F., Tholen, N.T.H., Ait El Maate, F., Brouwer, A.J., van Esse, G.W., Rijkers, D.T.S., Liskamp, R.M.J., and Pieters, R.J.
• College/School: College of Science and Engineering > School of Chemistry
• Journal Name: European Journal of Organic Chemistry
• Publisher: Wiley - V C H Verlag GmbH & Co. KGaA
• ISSN: 1434-193X
• ISSN (Online): 1099-0690