A general approach for the non-stop solid phase synthesis of TAC-scaffolded loops towards protein mimics containing discontinuous epitopes

Chamorro, C., Kruijtzer, J.A.W., Farsaraki, M., Balzarini, J. and Liskamp, R.M.J. (2009) A general approach for the non-stop solid phase synthesis of TAC-scaffolded loops towards protein mimics containing discontinuous epitopes. Chemical Communications(7), pp. 821-823. (doi:10.1039/b817357e)

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Abstract

In this Communication, the access to three different peptide loops attached to a small triazacyclophane (TAC) scaffold molecule for the mimicry of discontinuous epitopes present in, for example, antibodies is described for the first time.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Liskamp, Professor Robert
Authors: Chamorro, C., Kruijtzer, J.A.W., Farsaraki, M., Balzarini, J., and Liskamp, R.M.J.
College/School:College of Science and Engineering > School of Chemistry
Journal Name:Chemical Communications
ISSN:1359-7345
ISSN (Online):1364-548X

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