Baker, K.S. et al. (2013) Metagenomic study of the viruses of African straw-coloured fruit bats: detection of a chiropteran poxvirus and isolation of a novel adenovirus. Virology, 441(2), pp. 95-106. (doi: 10.1016/j.virol.2013.03.014)
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Abstract
Viral emergence as a result of zoonotic transmission constitutes a continuous public health threat. Emerging viruses such as SARS coronavirus, hantaviruses and henipaviruses have wildlife reservoirs. Characterising the viruses of candidate reservoir species in geographical hot spots for viral emergence is a sensible approach to develop tools to predict, prevent, or contain emergence events. Here, we explore the viruses of Eidolon helvum, an Old World fruit bat species widely distributed in Africa that lives in close proximity to humans. We identified a great abundance and diversity of novel herpes and papillomaviruses, described the isolation of a novel adenovirus, and detected, for the first time, sequences of a chiropteran poxvirus closely related with Molluscum contagiosum. In sum, E. helvum display a wide variety of mammalian viruses, some of them genetically similar to known human pathogens, highlighting the possibility of zoonotic transmission.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Murcia, Professor Pablo |
| Authors: | Baker, K.S., Leggett, R.M., Bexfield, N.H., Alston, M., Daly, G., Todd, S., Tachedjian, M., Holmes, C.E.G., Crameri, S., Wang, L.-F., Heeney, J.L., Suu-Ire, R., Kellam, P., Cunningham, A.A., Wood, J.L.N., Caccamo, M., and Murcia, P.R. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Infection & Immunity College of Medical Veterinary and Life Sciences > School of Infection & Immunity > Centre for Virus Research |
| Journal Name: | Virology |
| Publisher: | Elsevier |
| ISSN: | 0042-6822 |
| Published Online: | 04 April 2013 |
| Copyright Holders: | Copyright © 2013 Elsevier Ltd |
| First Published: | First published in Virology |
| Publisher Policy: | Reproduced in accordance with the copyright policy of the publisher |
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