Chitosan microparticles as injectable scaffolds for tissue engineering

García Cruz, D.M., Escobar Ivirico, J.L., Gomes, M.M., Gómez Ribelles, J.L., Salmerón-Sánchez, M. , Reis, R.L. and Mano, J.F. (2008) Chitosan microparticles as injectable scaffolds for tissue engineering. Journal of Tissue Engineering and Regenerative Medicine, 2(6), pp. 378-380. (doi:10.1002/term.106)

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Abstract

The use of chitosan microparticles as injectable carriers for cell transplantation represents a promising alternative to avoid the drawbacks of the implantation of other forms of three-dimensional (3D) scaffolds seeded with cells. In this study, a 3D construct is obtained in vitro by combining chitosan microparticles crosslinked with genipin and goat bone marrow stromal cells (GBMCs). Cell viability and the morphology of GBMCs were evaluated after culture for 7 and 14 days. Our results show the feasibility of chitosan microparticles as potential injectable scaffolds for tissue engineering and regenerative medicine.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Salmeron-Sanchez, Professor Manuel
Authors: García Cruz, D.M., Escobar Ivirico, J.L., Gomes, M.M., Gómez Ribelles, J.L., Salmerón-Sánchez, M., Reis, R.L., and Mano, J.F.
College/School:College of Science and Engineering > School of Engineering > Biomedical Engineering
Journal Name:Journal of Tissue Engineering and Regenerative Medicine
ISSN:1932-6254
ISSN (Online):1932-7005
Published Online:10 July 2008

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