Johnstone, S.R., Billaud, M., Lohman, A.W., Taddeo, E.P. and Isakson, B.E. (2012) Posttranslational modifications in connexins and pannexins. Journal of Membrane Biology, 245(5-6), pp. 319-332. (doi: 10.1007/s00232-012-9453-3)
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Abstract
Posttranslational modification is a common cellular process that is used by cells to ensure a particular protein function. This can happen in a variety of ways, e.g., from the addition of phosphates or sugar residues to a particular amino acid, ensuring proper protein life cycle and function. In this review, we assess the evidence for ubiquitination, glycosylation, phosphorylation, S-nitrosylation as well as other modifications in connexins and pannexin proteins. Based on the literature, we find that posttranslational modifications are an important component of connexin and pannexin regulation.
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Johnstone, Dr Scott |
Authors: | Johnstone, S.R., Billaud, M., Lohman, A.W., Taddeo, E.P., and Isakson, B.E. |
Subjects: | Q Science > Q Science (General) Q Science > QH Natural history > QH301 Biology Q Science > QH Natural history > QH345 Biochemistry |
College/School: | College of Medical Veterinary and Life Sciences > School of Cardiovascular & Metabolic Health |
Journal Name: | Journal of Membrane Biology |
ISSN: | 0022-2631 |
ISSN (Online): | 1432-1424 |
Published Online: | 28 June 2012 |
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