Duration of heart failure and the risk of atrial fibrillation: different mechanisms at different times?

Rankin, A.C. and Workman, A.J. (2009) Duration of heart failure and the risk of atrial fibrillation: different mechanisms at different times? Cardiovascular Research, 84(2), pp. 180-181. (doi: 10.1093/cvr/cvp299) (PMID:19713283) (PMCID:PMC2762576)

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Abstract

Chronic heart failure increases the risk of atrial fibrillation (AF), with the prevalence of AF paralleling the severity of heart failure.1 Factors that underlie this increased susceptibility to AF may include electrical, structural, and neurohumoral changes.2 In AF, it is recognized that atrial electrophysiological remodelling occurs and contributes to the perpetuation of the arrhythmia, most notably the decrease of effective refractory period (ERP) which predisposes to re-entry by shortening the wavelength. Does heart failure cause similar changes in atrial electrophysiology that predispose to the arrhythmia?

Item Type:Articles (Erratum)
Additional Information:Due to publisher embargo the full text of this paper will not be available until November 2010
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Workman, Dr Antony and Rankin, Professor Andrew
Authors: Rankin, A.C., and Workman, A.J.
Subjects:R Medicine > RC Internal medicine
College/School:College of Medical Veterinary and Life Sciences > School of Cardiovascular & Metabolic Health
College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing > Clinical Specialities
Journal Name:Cardiovascular Research
Publisher:Oxford University Press
ISSN:0008-6363
ISSN (Online):1755-3245
Published Online:27 August 2009
Copyright Holders:Copyright © 2009 The Authors
First Published:First published in Cardiovascular Research 84(2):180-181
Publisher Policy:Reproduced in accordance with the copyright policy of the publisher.

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