Linear assemblies of magnetic nanoparticles as MRI contrast agents

Corr, S.A., Byrne, S.J., Tekoriute, R., Meledandri, C.J., Brougham, D.F., Lynch, M., Kerskens, C., O'Dwyer, L. and Gun'ko, Y.K. (2008) Linear assemblies of magnetic nanoparticles as MRI contrast agents. Journal of the American Chemical Society, 130(13), pp. 4214-4215. (doi: 10.1021/ja710172z)

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Abstract

Using a one-step procedure we have prepared magnetic fluids comprising of polyelectrolyte stabilized magnetite nanoparticles. These nanocomposites are comprised of linear, chain-like assemblies of magnetic nanoparticles, which can be aligned in parallel arrays by an external magnetic field. We have shown the potential use of these materials as contrast agents by measuring their MR response in live rats. The new magnetic fluids have demonstrated good biocompatibility and potential for in vivo MRI diagnostics.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Corr, Professor Serena
Authors: Corr, S.A., Byrne, S.J., Tekoriute, R., Meledandri, C.J., Brougham, D.F., Lynch, M., Kerskens, C., O'Dwyer, L., and Gun'ko, Y.K.
College/School:College of Science and Engineering > School of Chemistry
Journal Name:Journal of the American Chemical Society
Publisher:American Chemical Society
ISSN:0002-7863
Published Online:11 March 2008

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