Crystallization and preliminary structural studies of champedak galactose-binding lectin

Gabrielsen, M., Riboldi-Tunnicliffe, A., Abdul-Rahman, P.S., Mohamed, E., Ibrahim, W.I.W., Hashim, O.H., Isaacs, N.W. and Cogdell, R.J. (2009) Crystallization and preliminary structural studies of champedak galactose-binding lectin. Acta Crystallographica. Section F: Structural Biology and Crystallization Communications, 65(9), pp. 895-897. (doi:10.1107/S1744309109029303)

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Publisher's URL: http://dx.doi.org/10.1107/S1744309109029303

Abstract

Galactose-binding lectin from champedak (Artocarpus integer) consists of two chains: [alpha] and [beta] (133 and 21 amino acids, respectively). It has been shown to recognize and bind to carbohydrates involved in IgA and C1 inhibitor molecules. The protein was purified and crystallized at 293 K. Crystals were observed in two space groups, P2<sub>1</sub> and P2<sub>1</sub>2<sub>1</sub>2, and diffracted to 1.65 and 2.6 Å, respectively.

Item Type:Articles
Keywords:Lectins, artocarpus integer, champedak, galactose binding
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Riboldi-Tunnicliffe, Dr Alan and Cogdell, Professor Richard and Isaacs, Professor Neil and Gabrielsen, Dr Mads
Authors: Gabrielsen, M., Riboldi-Tunnicliffe, A., Abdul-Rahman, P.S., Mohamed, E., Ibrahim, W.I.W., Hashim, O.H., Isaacs, N.W., and Cogdell, R.J.
Subjects:Q Science > QH Natural history > QH345 Biochemistry
College/School:College of Medical Veterinary and Life Sciences > Institute of Molecular Cell and Systems Biology
College of Science and Engineering > School of Chemistry
Journal Name:Acta Crystallographica. Section F: Structural Biology and Crystallization Communications
Publisher:Wiley-Blackwell Publishing, Inc.
ISSN:1744-3091
ISSN (Online):1744-3091

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