Use of single-molecule spectroscopy to tackle fundamental problems in biochemistry: using studies on purple bacterial antenna complexes as an example

Cogdell, R. J. and Kohler, J. (2009) Use of single-molecule spectroscopy to tackle fundamental problems in biochemistry: using studies on purple bacterial antenna complexes as an example. Biochemical Journal, 422(2), pp. 193-205. (doi:10.1042/BJ20090674)

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Publisher's URL: http://www.biochemj.org/bj/422/0193/bj4220193.htm

Abstract

Optical single-molecule techniques can be used in two modes to investigate fundamental questions in biochemistry, namely single-molecule detection and single-molecule spectroscopy. This review provides an overview of how single-molecule spectroscopy can be used to gain detailed information on the electronic structure of purple bacterial antenna complexes and to draw conclusions about the underlying physical structure. This information can be used to understand the energy-transfer reactions that are responsible for the earliest reactions in photosynthesis.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Cogdell, Professor Richard
Authors: Cogdell, R. J., and Kohler, J.
Subjects:Q Science > QH Natural history > QH345 Biochemistry
College/School:College of Medical Veterinary and Life Sciences > Institute of Molecular Cell and Systems Biology
Journal Name:Biochemical Journal
Journal Abbr.:Biochem. J.
Publisher:Portland Press Ltd.
ISSN:0264-6021
ISSN (Online):1470-8728
Published Online:13 August 2009

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
480721single molecule studies on purple bacterial antenna complexesRichard CogdellBiotechnology and Biological Sciences Research Council (BBSRC)BB/G003831/1RI MOLECULAR CELL & SYSTEMS BIOLOGY