A compact holographic optical tweezers instrument

Gibson, G.M. , Bowman, R.W., Linnenberger, A., Dienerowitz, M., Phillips, D., Carberry, D.M., Miles, M.J. and Padgett, M.J. (2012) A compact holographic optical tweezers instrument. Review of Scientific Instruments, 83(11), p. 113107. (doi: 10.1063/1.4768303)

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Publisher's URL: http://dx.doi.org/10.1063/1.4768303

Abstract

Holographic optical tweezers have found many applications including the construction of complex micron-scale 3D structures and the control of tools and probes for position, force, and viscosity measurement. We have developed a compact, stable, holographic optical tweezers instrument which can be easily transported and is compatible with a wide range of microscopy techniques, making it a valuable tool for collaborative research. The instrument measures approximately 30×30×35 cm and is designed around a custom inverted microscope, incorporating a fibre laser operating at 1070 nm. We designed the control software to be easily accessible for the non-specialist, and have further improved its ease of use with a multi-touch iPad interface. A high-speed camera allows multiple trapped objects to be tracked simultaneously. We demonstrate that the compact instrument is stable to 0.5 nm for a 10 s measurement time by plotting the Allan variance of the measured position of a trapped 2 μm silica bead. We also present a range of objects that have been successfully manipulated.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Dienerowitz, Dr Maria and Gibson, Dr Graham and Phillips, Dr David and Bowman, Mr Richard and Padgett, Professor Miles
Authors: Gibson, G.M., Bowman, R.W., Linnenberger, A., Dienerowitz, M., Phillips, D., Carberry, D.M., Miles, M.J., and Padgett, M.J.
College/School:College of Science and Engineering > School of Physics and Astronomy
Journal Name:Review of Scientific Instruments
Journal Abbr.:Rev. Sci. Instrum.
Publisher:American Institute of Physics
ISSN:0034-6748
ISSN (Online):1089-7623
Published Online:28 November 2012
First Published:First published in Review of Scientific Instruments 83(11):113107
Publisher Policy:Reproduced in accordance with the copyright policy of the publisher

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