The application of isoelectric focusing to routine screening for paraproteinaemia

Sinclair, D., Kumararatne, D.S., Forrester, J.B., Lamont, A. and Stott, D.I. (1983) The application of isoelectric focusing to routine screening for paraproteinaemia. Journal of Immunological Methods, 64(1-2), pp. 147-156. (doi:10.1016/0022-1759(83)90393-9)

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Abstract

We present a scheme for routine screening of patients' sera for monoclonal immunoglobulin by isoelectric focusing in agarose gels. Using this method combined with immunofixation, we have been able to detect monoclonal immunoglobulin in the sera of patients, and to identify the isotype of the immunoglobulin when conventional techniques such as zonal and immunoelectrophoresis have yielded equivocal results.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Stott, Professor David
Authors: Sinclair, D., Kumararatne, D.S., Forrester, J.B., Lamont, A., and Stott, D.I.
College/School:College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation
Journal Name:Journal of Immunological Methods
Publisher:Elsevier
ISSN:0022-1759

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