Asymmetric synthesis of pipecolic acid and derivatives

Sutherland, A. and Cant, A. (2012) Asymmetric synthesis of pipecolic acid and derivatives. Synthesis, 44(13), pp. 1935-1950. (doi: 10.1055/s-0031-1289767)

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The nonproteinogenic α-amino acid, l-pipecolic acid and its derivatives are components of a wide range of pharmacologically active compounds. The significant biological activity of these compounds has resulted in the development of many synthetic approaches for their preparation. This review highlights these key methods as well as the application of these compounds for the preparation of enzyme inhibitors, conformationally restricted building blocks and peptidomimetics.

Item Type:Articles
Glasgow Author(s) Enlighten ID:Cant, Mr Alastair and Sutherland, Professor Andrew
Authors: Sutherland, A., and Cant, A.
College/School:College of Science and Engineering > School of Chemistry
Journal Name:Synthesis
Publisher:Georg Thieme Verlag
ISSN (Online):1437-210X
Published Online:25 May 2012

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