Interpreting human follicular recruitment and antimüllerian hormone concentrations throughout life

Fleming, R., Kelsey, T.W., Anderson, R.A., Wallace, W.H. and Nelson, S.M. (2012) Interpreting human follicular recruitment and antimüllerian hormone concentrations throughout life. Fertility and Sterility, 98(5), pp. 1097-1102. (doi:10.1016/j.fertnstert.2012.07.1114)

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Abstract

The changes in the relationships between circulating antimüllerian hormone, the size of the primordial follicle pool, and follicular recruitment before and through the reproductive years have now been clarified, and show dynamic changes through sexual development. The constant relationship between the number of follicles and circulating antimüllerian hormone exists only after the age of 25 years, implying that the association between follicular recruitment and follicular survival to the later stages of development is not constant across the reproductive life course. This commentary assesses the factors that may underlie these relationships and their clinical implications for reproductive health.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Nelson, Professor Scott and Fleming, Professor Richard
Authors: Fleming, R., Kelsey, T.W., Anderson, R.A., Wallace, W.H., and Nelson, S.M.
College/School:College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing
Journal Name:Fertility and Sterility
ISSN:0015-0282

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