Patterning of microspheres and microbubbles in an acoustic tweezers

Bernassau, A.L., MacPherson, P.G.A., Beeley, J., Drinkwater, B.W. and Cumming, D.R.S. (2013) Patterning of microspheres and microbubbles in an acoustic tweezers. Biomedical Microdevices, 5(2), pp. 289-297. (doi:10.1007/s10544-012-9729-5)

Bernassau, A.L., MacPherson, P.G.A., Beeley, J., Drinkwater, B.W. and Cumming, D.R.S. (2013) Patterning of microspheres and microbubbles in an acoustic tweezers. Biomedical Microdevices, 5(2), pp. 289-297. (doi:10.1007/s10544-012-9729-5)

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Abstract

We describe the construction of an ultrasonic device capable of micro-patterning a range of microscopic particles for bioengineering applications such as targeted drug delivery. The device is formed from seven ultrasonic transducers positioned around a heptagonal cavity. By exciting two or three transducers simultaneously, lines or hexagonal shapes can be formed with microspheres, emulsions and microbubbles. Furthermore, phase control of the transducers allows patterning at any desired position in a controlled manner. The paper discusses in detail direct positioning of functionalised microspheres, emulsions and microbubbles. With the advantages of miniaturization, rapid and simple fabrication, ultrasonic tweezers is a potentially useful tool in many biomedical applications.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Cumming, Professor David and Bernassau, Dr Anne and Beeley, Mr James
Authors: Bernassau, A.L., MacPherson, P.G.A., Beeley, J., Drinkwater, B.W., and Cumming, D.R.S.
College/School:College of Science and Engineering > School of Engineering > Electronics and Nanoscale Engineering
Journal Name:Biomedical Microdevices
Publisher:Springer Link
ISSN:1387-2176
ISSN (Online):1572-8781
Published Online:09 December 2012

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