Targett-Adams, P., Boulant, S., Douglas, M. W. and McLauchlan, J. (2010) Lipid metabolism and HCV infection. Viruses, 2(5), pp. 1195-1217. (doi: 10.3390/v2051195) (PMID:21994676) (PMCID:PMC3187597)
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Abstract
Chronic infection by hepatitis C virus (HCV) can lead to severe liver disease and is a global healthcare problem. The liver is highly metabolically active and one of its key functions is to control the balance of lipid throughout the body. A number of pathologies have been linked to the impact of HCV infection on liver metabolism. However, there is also growing evidence that hepatic metabolic processes contribute to the HCV life cycle. This review summarizes the relationship between lipid metabolism and key stages in the production of infectious HCV.
| Item Type: | Articles |
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| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Targett-Adams, Dr Paul and McLauchlan, Professor John |
| Authors: | Targett-Adams, P., Boulant, S., Douglas, M. W., and McLauchlan, J. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Infection & Immunity College of Medical Veterinary and Life Sciences > School of Infection & Immunity > Centre for Virus Research |
| Journal Name: | Viruses |
| Publisher: | MDPI |
| ISSN: | 1999-4915 |
| ISSN (Online): | 1999-4915 |
| Published Online: | 11 May 2010 |
| Copyright Holders: | Copyright © 2010 The Authors |
| First Published: | First published in Viruses 2(5):1195-1217 |
| Publisher Policy: | Reproduced in accordance with the copyright policy of the publisher |
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