Murphy, D.J., Hernendez-Pinzon, I., Patel, K., Hope, R.G. and McLauchlan, J. (2000) New insights into the mechanisms of lipid-body biogenesis in plants and other organisms. Biochemical Society Transactions, 28(6), pp. 710-1. (doi: 10.1042/bst0280713)
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Abstract
A comparative approach has been used to study the role of several lipid-body-binding proteins in plants and animals. Caleosins are a newly discovered class of calcium-binding lipid-body proteins found in plants and fungi, which we now report to have separate endoplasmic reticulum- and lipid-body-associated isoforms. We also compare the lipid-body targeting of oleosin from plants and the core protein of the hepatitis C virus when they were expressed separately in lipid-accumulating animal cell lines. This is a novel and powerful approach to investigating the factors that determine the lipid-body targeting of a wide range of proteins.
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | McLauchlan, Professor John |
Authors: | Murphy, D.J., Hernendez-Pinzon, I., Patel, K., Hope, R.G., and McLauchlan, J. |
College/School: | College of Medical Veterinary and Life Sciences > School of Infection & Immunity College of Medical Veterinary and Life Sciences > School of Infection & Immunity > Centre for Virus Research |
Journal Name: | Biochemical Society Transactions |
ISSN: | 0300-5127 |
ISSN (Online): | 1470-8752 |
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