New insights into the mechanisms of lipid-body biogenesis in plants and other organisms

Murphy, D.J., Hernendez-Pinzon, I., Patel, K., Hope, R.G. and McLauchlan, J. (2000) New insights into the mechanisms of lipid-body biogenesis in plants and other organisms. Biochemical Society Transactions, 28(6), pp. 710-1. (doi:10.1042/bst0280713)

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Abstract

A comparative approach has been used to study the role of several lipid-body-binding proteins in plants and animals. Caleosins are a newly discovered class of calcium-binding lipid-body proteins found in plants and fungi, which we now report to have separate endoplasmic reticulum- and lipid-body-associated isoforms. We also compare the lipid-body targeting of oleosin from plants and the core protein of the hepatitis C virus when they were expressed separately in lipid-accumulating animal cell lines. This is a novel and powerful approach to investigating the factors that determine the lipid-body targeting of a wide range of proteins.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:McLauchlan, Professor John
Authors: Murphy, D.J., Hernendez-Pinzon, I., Patel, K., Hope, R.G., and McLauchlan, J.
College/School:College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation
Journal Name:Biochemical Society Transactions
ISSN:0300-5127
ISSN (Online):1470-8752

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