Whalley, J.M., Robertson, G.R., and Davison, A.J. (1981) Analysis of the genome of Equine Herpesvirus Type 1: Arrangement of cleavage sites for restriction Endonucleases EcoRI, BglII and BamHI. Journal of General Virology, 57 (2). pp. 307-323. ISSN 0022-1317 (doi:10.1099/0022-1317-57-2-307)
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Publisher's URL: http://dx.doi.org/10.1099/0022-1317-57-2-307
The genome of an Australian isolate of equine herpesvirus type 1 (equine abortion virus) has been analysed using the restriction endonucleases EcoRI, BglII and BamHI, and a physical map constructed. Terminal fragments were identified by exonuclease treatments, and linkage of fragments was deduced by a combination of single- and double-digest experiments and cross-blot hybridizations. The genome has a mol. wt. of 100 x 10 6 and is comprised of a short unique region bounded by repetitive sequences, which is present in both orientations in approximately equal amounts in the DNA population, and a long unique region existing in only one orientation.
|Glasgow Author(s):||Davison, Dr Andrew|
|Authors:||Whalley, J.M., Robertson, G.R., and Davison, A.J.|
|College/School:||College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation|
|Journal Name:||Journal of General Virology|
|Publisher:||Society for General Microbiology|