Koi herpesvirus represents a third cyprinid herpesvirus (CyHV-3)in the family Herpesviridae

Waltzek, T.B., Kelley, G.O., Stone, D.M., Way, K., Hanson, L., Fukuda, H., Hirono, I., Aoki, T., Davison, A.J. and Hedrick, R.P. (2005) Koi herpesvirus represents a third cyprinid herpesvirus (CyHV-3)in the family Herpesviridae. Journal of General Virology, 86(6), pp. 1659-1667. (doi:10.1099/vir.0.80982-0)

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Publisher's URL: http://dx.doi.org/10.1099/vir.0.80982-0

Abstract

The sequences of four complete genes were analysed in order to determine the relatedness of koi herpesvirus (KHV) to three fish viruses in the family Herpesviridae: carp pox herpesvirus (Cyprinid herpesvirus 1, CyHV-1), haematopoietic necrosis herpesvirus of goldfish (Cyprinid herpesvirus 2, CyHV-2) and channel catfish virus (Ictalurid herpesvirus 1, IcHV-1). The genes were predicted to encode a helicase, an intercapsomeric triplex protein, the DNA polymerase and the major capsid protein. The results showed that KHV is related closely to CyHV-1 and CyHV-2, and that the three cyprinid viruses are related, albeit more distantly, to IcHV-1. Twelve KHV isolates from four diverse geographical areas yielded identical sequences for a region of the DNA polymerase gene. These findings, with previously published morphological and biological data, indicate that KHV should join the group of related lower-vertebrate viruses in the family Herpesviridae under the formal designation Cyprinid herpesvirus 3 (CyHV-3).

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Davison, Professor Andrew
Authors: Waltzek, T.B., Kelley, G.O., Stone, D.M., Way, K., Hanson, L., Fukuda, H., Hirono, I., Aoki, T., Davison, A.J., and Hedrick, R.P.
College/School:College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation
Journal Name:Journal of General Virology
Journal Abbr.:J. Gen. Virol.
Publisher:Society for General Microbiology
ISSN:0022-1317
ISSN (Online):1465-2099

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