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The DNA sequence of adenovirus type 40

Davison, A.J., Telford, E.A.R., Watson, M.S., McBride, K., and Mautner, V. (1993) The DNA sequence of adenovirus type 40. Journal of Molecular Biology, 234 (4). pp. 1308-1316. ISSN 0022-2836 (doi:10.1006/jmbi.1993.1687)

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Abstract

The 34,214 bp DNA sequence of adenovirus type 40 strain Dugan was determined directly from random fragments of virion DNA cloned into a bacteriophage M13 cloning vector. The gene layout is similar to that of other human adenoviruses, and in addition contains two potential protein-coding regions that are conserved, but have not been recognized previously, in other adenovirus genomes. One is oriented rightward, contained within the intron in the protein-coding region for the L4 33K gene, and would encode a protein sharing N-terminal sequence with 33K. The other is a leftward oriented exon located between the E3 and L5 IV (fibre) regions which would specify the N terminus of a novel protein. The region encoding the C terminus of this protein is not apparent from sequence data.

Item Type:Article
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Davison, Dr Andrew
Authors: Davison, A.J., Telford, E.A.R., Watson, M.S., McBride, K., and Mautner, V.
College/School:College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation
Journal Name:Journal of Molecular Biology
ISSN:0022-2836

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