The DNA sequence of adenovirus type 40

Davison, A.J. , Telford, E.A.R., Watson, M.S., McBride, K. and Mautner, V. (1993) The DNA sequence of adenovirus type 40. Journal of Molecular Biology, 234(4), pp. 1308-1316. (doi:10.1006/jmbi.1993.1687)

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The 34,214 bp DNA sequence of adenovirus type 40 strain Dugan was determined directly from random fragments of virion DNA cloned into a bacteriophage M13 cloning vector. The gene layout is similar to that of other human adenoviruses, and in addition contains two potential protein-coding regions that are conserved, but have not been recognized previously, in other adenovirus genomes. One is oriented rightward, contained within the intron in the protein-coding region for the L4 33K gene, and would encode a protein sharing N-terminal sequence with 33K. The other is a leftward oriented exon located between the E3 and L5 IV (fibre) regions which would specify the N terminus of a novel protein. The region encoding the C terminus of this protein is not apparent from sequence data.

Item Type:Articles
Glasgow Author(s) Enlighten ID:Davison, Professor Andrew
Authors: Davison, A.J., Telford, E.A.R., Watson, M.S., McBride, K., and Mautner, V.
College/School:College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation
Journal Name:Journal of Molecular Biology

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