Optoelectronic tweezers for medical diagnostics

Kremer, C., Neale, S. , Menachery, A., Barrett, M. and Cooper, J.M. (2012) Optoelectronic tweezers for medical diagnostics. Proceedings of the SPIE: The International Society for Optical Engineering, 8212, 82120E. (doi:10.1117/12.903944)

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Abstract

Optoelectronic tweezers (OET) allows the spatial patterning of electric fields through selected illumination of a photoconductive surface. This enables the manipulation of micro particles and cells by creating non-uniform electrical fields that then produce dielectrophoretic (DEP) forces. The DEP responses of cells differ and can produce negative or positive (repelled or attracted to areas of high electric field) forces. Therefore OET can be used to manipulate individual cells and separate different cell types from each other. Thus OET has many applications for medical diagnostics, demonstrated here with work towards diagnosing Human African Trypanosomiasis, also known as sleeping sickness.

Item Type:Articles
Additional Information:Frontiers in Biological Detection: From Nanosensors to Systems IV, San Francisco, USA, 21 Jan 2012
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Cooper, Professor Jonathan and Menachery, Dr Anoop and Neale, Dr Steven
Authors: Kremer, C., Neale, S., Menachery, A., Barrett, M., and Cooper, J.M.
College/School:College of Science and Engineering > School of Engineering > Biomedical Engineering
Journal Name:Proceedings of the SPIE: The International Society for Optical Engineering
Publisher:SPIE - The International Society for Optical Engineering
ISSN:0277-786X

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