Maki, A., Kono, H., Gupta, M. , Asakawa, M., Suzuki, T., Matsuda, M., Fujii, H. and Rusyn, I. (2007) Predictive power of biomarkers of oxidative stress and inflammation in patients with hepatitis C virus-associated hepatocellular carcinoma. Annals of Surgical Oncology, 14(3), pp. 1182-1190. (doi: 10.1245/s10434-006-9049-1)
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Abstract
These results support the hypothesis that HCV-induced inflammation causes oxidative DNA damage and promotes hepatocarcinogenesis which directly affects the clinical outcome. Since patients with greater intra-hepatic oxidative stress had a higher incidence of HCC recurrence, we suggest that oxidative stress biomarkers could potentially be used as a useful clinical diagnostic tool to predict the duration of disease-free survival in patients with HCV-associated HCC.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Gupta, Professor Mayetri |
| Authors: | Maki, A., Kono, H., Gupta, M., Asakawa, M., Suzuki, T., Matsuda, M., Fujii, H., and Rusyn, I. |
| College/School: | College of Science and Engineering > School of Mathematics and Statistics > Statistics |
| Journal Name: | Annals of Surgical Oncology |
| ISSN: | 1068-9265 |
| ISSN (Online): | 1534-4681 |
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