Acute phase proteins in ruminants

Ceciliani, F., Ceron, J.J., Eckersall, P.D. and Sauerwein, H. (2012) Acute phase proteins in ruminants. Journal of Proteomics, 75(14), pp. 4207-4231. (doi: 10.1016/j.jprot.2012.04.004)

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The physiological response to infections and injuries involves local inflammation and the initiation of events leading to a systemic response, also called acute phase reaction (APR). This multiplicity of changes is distant from the site of injury, and includes fever, leukocytosis and quantitative and qualitative modification of a group of non-structurally related proteins present in blood and other biological fluids, collectively named Acute Phase Proteins (APP). Proteomic investigations of serum or plasma following natural or experimental infection frequently reveal substantial alterations in the APP, several of which are high abundance proteins in these fluids.

Item Type:Articles
Glasgow Author(s) Enlighten ID:Eckersall, Professor David
Authors: Ceciliani, F., Ceron, J.J., Eckersall, P.D., and Sauerwein, H.
College/School:College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation
Journal Name:Journal of Proteomics
Published Online:11 April 2012

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