Feline leukaemia virus: half a century since its discovery

Willett, B.J. and Hosie, M.J. (2013) Feline leukaemia virus: half a century since its discovery. Veterinary Journal, 195(1), pp. 16-23. (doi: 10.1016/j.tvjl.2012.07.004)

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Publisher's URL: http://dx.doi.org/10.1016/j.tvjl.2012.07.004


In the early 1960s, Professor William (Bill) F.H. Jarrett was presented with a timeGÇôspace cluster of cats with lymphoma identified by a local veterinary practitioner, Harry Pfaff, and carried out experiments to find if the condition might be caused by a virus, similar to lymphomas noted previously in poultry and mice. In 1964, the transmission of lymphoma in cats and the presence of virus-like particles that resembled GÇÿthe virus of murine leukaemiasGÇÖ in the induced tumours were reported in Nature. These seminal studies initiated research on feline leukaemia virus (FeLV) and launched the field of feline retrovirology. This review article considers the way in which some of the key early observations made by Bill Jarrett and his coworkers have developed in subsequent years and discusses progress that has been made in the field since FeLV was first discovered.

Item Type:Articles
Additional Information:NOTICE: this is the author’s version of a work that was accepted for publication in Veterinary Journal. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Veterinary Journal [vol, no, date]. DOI: 10.1016/j.tvjl.2012.07.004
Glasgow Author(s) Enlighten ID:Hosie, Professor Margaret and Willett, Professor Brian
Authors: Willett, B.J., and Hosie, M.J.
College/School:College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation
College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation > Centre for Virus Research
Journal Name:Veterinary Journal
Publisher:Elsevier Ltd
Published Online:03 August 2012
Copyright Holders:Copyright © 2012 Elsevier
First Published:First published in Veterinary Journal 2012
Publisher Policy:Reproduced in accordance with the copyright policy of the publisher
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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
363381Rational Design of a Lentiviral VaccineMargaret HosieMedical Research Council (MRC)G0300387MVLS III - CENTRE FOR VIRUS RESEARCH