Mirchandani, A. S., Salmond, R. J. and Liew, F. Y. (2012) Interleukin-33 and the function of innate lymphoid cells. Trends in Immunology, 33(8), pp. 389-396. (doi: 10.1016/j.it.2012.04.005)
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Publisher's URL: http://dx.doi.org/10.1016/j.it.2012.04.005
Abstract
Interleukin (IL)-33 is a member of the IL-1 cytokine family that has been shown to play an important role in the induction and effector phases of type 2 immune responses. Both innate and adaptive immunity are regulated by IL-33, and many studies have shown disease-associated functions for this cytokine. Recently, IL-33 has been implicated in the function of novel innate lymphocyte populations that regulate both protective responses in parasitic infections and allergic airway inflammation. Here, we discuss recent data highlighting the dual roles of IL-33 in protective and deleterious immune responses.
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Liew, Prof Foo and Mirchandani, Dr Ananda and Salmond, Dr Robert |
Authors: | Mirchandani, A. S., Salmond, R. J., and Liew, F. Y. |
College/School: | College of Medical Veterinary and Life Sciences > School of Infection & Immunity |
Journal Name: | Trends in Immunology |
Publisher: | Elsevier |
ISSN: | 1471-4906 |
ISSN (Online): | 1471-4981 |
Published Online: | 18 May 2012 |
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