Relationship between oxidative stress and circulating testosterone and cortisol in pre-spawning female brown trout

Hoogenboom, M.O., Metcalfe, N.B. , Groothuis, T.G.G., de Vries, B. and Costantini, D. (2012) Relationship between oxidative stress and circulating testosterone and cortisol in pre-spawning female brown trout. Comparative Biochemistry and Physiology. Part A: Molecular and Integrative Physiology, 163(3-4), pp. 379-387. (doi:10.1016/j.cbpa.2012.07.002)

Full text not currently available from Enlighten.

Publisher's URL: http://dx.doi.org/10.1016/j.cbpa.2012.07.002

Abstract

Reproduction in vertebrates is an energy-demanding process that is mediated by endogenous hormones and potentially results in oxidative stress. The primary aim of this study was to quantify the relationship between oxidative stress parameters (antioxidant capacity and levels of reactive oxygen metabolites) and circulating testosterone and cortisol in a common and widespread teleost fish, the brown trout (Salmo trutta, L.). Results show that trout with higher testosterone levels prior to spawning have higher levels of oxidative damage at the time that they spawn (although by the time of spawning testosterone levels had dropped, leading to a negative relationship between testosterone and oxidative damage at that time). Cortisol levels were not directly related to oxidative damage or antioxidant capacity, but concentrations of this hormone were positively related to levels of fungal infection, which was itself associated both with lower antioxidant capacity and lower levels of oxidative damage. These results highlight the complexity of interactions between different components of the endocrine system and metabolism and suggest that caution be used in interpreting relationships between a single hormone and indicators of oxidative balance or other fitness proxies.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Costantini, Dr David and Hoogenboom, Ms Mia and Metcalfe, Professor Neil
Authors: Hoogenboom, M.O., Metcalfe, N.B., Groothuis, T.G.G., de Vries, B., and Costantini, D.
College/School:College of Medical Veterinary and Life Sciences > Institute of Biodiversity Animal Health and Comparative Medicine
Journal Name:Comparative Biochemistry and Physiology. Part A: Molecular and Integrative Physiology
ISSN:1095-6433
ISSN (Online):1531-4332
Published Online:26 July 2012

University Staff: Request a correction | Enlighten Editors: Update this record

Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
529351Does poor maternal condition reduce early offspring performance in the wild?Neil MetcalfeNatural Environment Research Council (NERC)NERCRI BIODIVERSITY ANIMAL HEALTH & COMPMED
477571The causes and consequences of intraspecific variation in standard metabolic rateNeil MetcalfeNatural Environment Research Council (NERC)NE/F019165/1RI BIODIVERSITY ANIMAL HEALTH & COMPMED