Martino, C., Kim, S.-H., Horsfall, L., Abbaspourrad, A., Rosser, S.J., Cooper, J. and Weitz, D.A. (2012) Protein expression, aggregation, and triggered release from polymersomes as artificial cell-like structures. Angewandte Chemie (International Edition), 51(26), pp. 6416-6420. (doi: 10.1002/anie.201201443)
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Abstract
Bringing droplets to life: A cytoskeletal protein (red dots, see scheme) is expressed in artificial cells composed of biocompatible polymersomes, which encapsulate expression machinery and amino acid building blocks. Release of the expressed proteins can be triggered by a negative osmotic shock.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Rosser, Professor Susan and Horsfall, Dr Louise and Cooper, Professor Jonathan |
| Authors: | Martino, C., Kim, S.-H., Horsfall, L., Abbaspourrad, A., Rosser, S.J., Cooper, J., and Weitz, D.A. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Cardiovascular & Metabolic Health College of Science and Engineering > School of Engineering > Biomedical Engineering |
| Journal Name: | Angewandte Chemie (International Edition) |
| Journal Abbr.: | Angew Chem Int Ed Engl |
| Publisher: | Wiley - V C H Verlag GmbH & Co. KGaA |
| ISSN: | 1433-7851 |
| ISSN (Online): | 1521-3773 |
| Published Online: | 29 May 2012 |
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