Protein expression, aggregation, and triggered release from polymersomes as artificial cell-like structures

Martino, C., Kim, S.-H., Horsfall, L., Abbaspourrad, A., Rosser, S.J., Cooper, J. and Weitz, D.A. (2012) Protein expression, aggregation, and triggered release from polymersomes as artificial cell-like structures. Angewandte Chemie (International Edition), 51(26), pp. 6416-6420. (doi:10.1002/anie.201201443)

Full text not currently available from Enlighten.

Abstract

Bringing droplets to life: A cytoskeletal protein (red dots, see scheme) is expressed in artificial cells composed of biocompatible polymersomes, which encapsulate expression machinery and amino acid building blocks. Release of the expressed proteins can be triggered by a negative osmotic shock.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Rosser, Professor Susan and Horsfall, Dr Louise and Cooper, Professor Jonathan
Authors: Martino, C., Kim, S.-H., Horsfall, L., Abbaspourrad, A., Rosser, S.J., Cooper, J., and Weitz, D.A.
College/School:College of Medical Veterinary and Life Sciences > Institute of Cardiovascular and Medical Sciences
College of Science and Engineering > School of Engineering > Biomedical Engineering
Journal Name:Angewandte Chemie (International Edition)
Journal Abbr.:Angew Chem Int Ed Engl
Publisher:Wiley - V C H Verlag GmbH & Co. KGaA
ISSN:1433-7851
ISSN (Online):1521-3773
Published Online:29 May 2012

University Staff: Request a correction | Enlighten Editors: Update this record