Bache, R.A., Gray, W.M., and Murray-Smith, D.J. (1981) Time-domain system identification applied to noninvasive estimation of cardiopulmonary quantities. IEE Proceedings: Control Theory and Applications, 128(2), pp. 56-64. (doi:10.1049/ip-d:19810010)
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The paper describes an application of system identification techniques to the estimation of cardiac output and other cardiopulmonary quantities in human subjects. The method used requires continuous measurement of gas flow rates and gas concentration at the subject's mouth and involves the use of a lumped parameter model of the gas exchange processes. Particular emphasis is given to investigation of the identifiability and determinancy of the model and to important questions of the choice of input test signal. Estimation of the parameters of this model is by an extension of the maximum likelihood method of Astrom and Bohlin. This paper includes a summary of some encouraging results which have been obtained using this approach.
|Keywords:||Biomedical engineering, modelling, simulation, signal synthesis, system identification|
|Glasgow Author(s) Enlighten ID:||Murray-Smith, Professor David|
|Authors:||Bache, R.A., Gray, W.M., and Murray-Smith, D.J.|
|Subjects:||Q Science > QP Physiology|
R Medicine > R Medicine (General)
T Technology > TJ Mechanical engineering and machinery
T Technology > TK Electrical engineering. Electronics Nuclear engineering
|College/School:||College of Science and Engineering > School of Engineering > Systems Power and Energy|
|Journal Name:||IEE Proceedings: Control Theory and Applications|
|Publisher:||Institution of Engineering and Technology|
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