Application of terahertz spectroscopy to the characterization of biological samples using birefringence silicon grating

Saha, S.C., Grant, J.P. , Khalid, A. and Cumming, D. (2012) Application of terahertz spectroscopy to the characterization of biological samples using birefringence silicon grating. Journal of Biomedical Optics, 17, 067006. (doi:10.1117/1.JBO.17.6.067006)

Saha, S.C., Grant, J.P. , Khalid, A. and Cumming, D. (2012) Application of terahertz spectroscopy to the characterization of biological samples using birefringence silicon grating. Journal of Biomedical Optics, 17, 067006. (doi:10.1117/1.JBO.17.6.067006)

[img] Text
65873.pdf

1MB

Publisher's URL: http://dx.doi.org/10.1117/1.JBO.17.6.067006

Abstract

We present a device and method for performing vector transmission spectroscopy on biological specimens at terahertz (THz) frequencies. The device consists of artificial dielectric birefringence obtained from silicon microfluidic grating structures. The device can measure the complex dielectric function of a liquid, across a wide THz band of 2 to 5.5 THz, using a Fourier transform infrared spectrometer. Measurement data from a range of liquid specimens, including sucrose, salmon deoxyribonucleic acid (DNA), herring DNA, and bovine serum albumin protein solution in water are presented. The specimen handling is simple, using a microfluidic channel. The transmission through the device is improved significantly and thus the measurement accuracy and bandwidth are increased

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Saha, Dr Shimul and Cumming, Professor David and Khalid, Dr Ata-ul-Habib and Grant, Dr James
Authors: Saha, S.C., Grant, J.P., Khalid, A., and Cumming, D.
College/School:College of Science and Engineering > School of Engineering > Electronics and Nanoscale Engineering
Journal Name:Journal of Biomedical Optics
Publisher:Society of Photo-optical Instrumentation Engineers
ISSN:1083-3668
ISSN (Online):1560-2281
Copyright Holders:Copyright © 2012 SPIE
First Published:First published in Journal of Biomedical Optics 17:067006
Publisher Policy:Reproduced in accordance with the copyright policy of the publisher

University Staff: Request a correction | Enlighten Editors: Update this record

Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
449212TeraHertz planar Gunn diodesDavid CummingEngineering & Physical Sciences Research Council (EPSRC)EP/F014791/1ENG - ENGINEERING ELECTRONICS & NANO ENG