Age- and sex-specific trends in fatal incidence and hospitalized incidence of stroke in Scotland, 1986 to 2005

Lewsey, J. et al. (2009) Age- and sex-specific trends in fatal incidence and hospitalized incidence of stroke in Scotland, 1986 to 2005. Circulation: Cardiovascular Quality and Outcomes, 2(5), pp. 475-483. (doi:10.1161/CIRCOUTCOMES.108.825968)

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Abstract

<b>Background</b>: Temporal trends in stroke incidence are unclear. We aimed to examine age- and sex-specific temporal trends in incidence of fatal and nonfatal hospitalized stroke in Scotland from 1986 to 2005. <b>Methods and Results</b>: Mean age at the time of first stroke was 70.8 (SD, 12.9) years in men and 76.4 (12.9) years in women. Between 1986 and 2005, rates fell in men from 235 (95% CI, 229 to 242) to 149 (144 to 154) and in women from 299 (292 to 306) to 182 (177 to 188). Poisson modeling showed that temporal trends were influenced by age with declines in incidence of hospitalized stroke starting later in younger than older age groups. In both men and women aged under 55 years, the overall incidence rate of stroke was significantly higher in 2005 than in 1986. <b>Conclusions</b>: We report in a whole country that the overall incidence of stroke declined steadily and substantially between 1986 and 2005, with a relative reduction in the risk of stroke of 31% in men and 42% in women. Reductions in rates of both hospitalized and nonhospitalized fatal stroke contributed to this overall decline. The increase in incident stroke rates in young people is of concern.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Lewsey, Professor Jim and Capewell, Dr Simon and McMurray, Professor John and Walters, Professor Matthew and MacIntyre, Dr Kate and Langhorne, Professor Peter and Jhund, Dr Pardeep and Briggs, Professor Andrew and Gillies, Dr Michelle
Authors: Lewsey, J., Jhund, P.S., Gillies, M., Chalmers, J.W.T., Redpath, A., Kelso, L., Briggs, A., Walters, M., Langhorne, P., Capewell, S., McMurray, J.J.V., and MacIntyre, K.
Subjects:R Medicine > RC Internal medicine
College/School:College of Medical Veterinary and Life Sciences > Institute of Health and Wellbeing > Public Health
College of Medical Veterinary and Life Sciences > Institute of Health and Wellbeing > Health Economics and Health Technology Assessment
College of Medical Veterinary and Life Sciences > Institute of Cardiovascular and Medical Sciences
College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing > Centre for Population and Health Sciences
Journal Name:Circulation: Cardiovascular Quality and Outcomes
ISSN:1941-7713
ISSN (Online):1941-7705
Published Online:21 July 2009

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