Evaluation of a mobile phone-based, advanced symptom management system (ASyMS©) in the management of chemotherapy-related toxicity

Kearney, N., McCann, L., Norrie, J., Taylor, L., Gray, P., McGee-Lennon, M., Sage, M., Miller, M. and Maguire, R. (2009) Evaluation of a mobile phone-based, advanced symptom management system (ASyMS©) in the management of chemotherapy-related toxicity. Supportive Care in Cancer, 17(4), pp. 437-444. (doi: 10.1007/s00520-008-0515-0) (PMID:18953579)

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Abstract

Objectives To evaluate the impact of a mobile phone-based, remote monitoring, advanced symptom management system (ASyMS©) on the incidence, severity and distress of six chemotherapy-related symptoms (nausea, vomiting, fatigue, mucositis, hand–foot syndrome and diarrhoea) in patients with lung, breast or colorectal cancer.<p></p> Design A two group (intervention and control) by five time points (baseline, pre-cycle 2, pre-cycle 3, pre-cycle 4 and pre-cycle 5) randomised controlled trial.<p></p> Setting Seven clinical sites in the UK; five specialist cancer centres and two local district hospitals.<p></p> Participants One hundred and twelve people with breast, lung or colorectal cancer receiving outpatient chemotherapy. Interventions A mobile phone-based, remote monitoring, advanced symptom management system (ASyMS©).<p></p> Main outcome measures Chemotherapy-related morbidity of six common chemotherapy-related symptoms (nausea, vomiting, fatigue, mucositis, hand–foot syndrome and diarrhoea). Results There were significantly higher reports of fatigue in the control group compared to the intervention group (odds ratio = 2.29, 95%CI = 1.04 to 5.05, P = 0.040) and reports of hand–foot syndrome were on average lower in the control group (odds ratio control/intervention = 0.39, 95%CI = 0.17 to 0.92, P = 0.031).<p></p> Conclusion The study demonstrates that ASyMS© can support the management of symptoms in patients with lung, breast and colorectal cancer receiving chemotherapy.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:McGee-Lennon, Dr Marilyn and Gray, Mr Philip and Norrie, Prof John
Authors: Kearney, N., McCann, L., Norrie, J., Taylor, L., Gray, P., McGee-Lennon, M., Sage, M., Miller, M., and Maguire, R.
College/School:College of Medical Veterinary and Life Sciences > Institute of Health and Wellbeing > Robertson Centre
College of Science and Engineering > School of Computing Science
Journal Name:Supportive Care in Cancer
Publisher:Springer
ISSN:0941-4355
ISSN (Online):1433-7339
Published Online:25 October 2008

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