Statin therapy and the acute inflammatory response after coronary artery bypass grafting

Brull, D.J., Sanders, J., Rumley, A., Lowe, G.D.O., Humphries, S.E. and Montgomery, H.E. (2001) Statin therapy and the acute inflammatory response after coronary artery bypass grafting. American Journal of Cardiology, 88(4), pp. 431-433. (doi: 10.1016/S0002-9149(01)01696-4)

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Publisher's URL: http://dx.doi.org/10.1016/S0002-9149(01)01696-4

Abstract

Preoperative statin therapy has been shown to improve cardiovascular outcome after coronary artery bypass grafting; however, the clinical gain achieved is in excess of the reduction in lipids. We demonstrate that statin therapy exerts a direct anti-inflammatory effect mediated through reduced interleukin-6 production.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Rumley, Dr Ann and Lowe, Professor Gordon
Authors: Brull, D.J., Sanders, J., Rumley, A., Lowe, G.D.O., Humphries, S.E., and Montgomery, H.E.
Subjects:R Medicine > RC Internal medicine
College/School:College of Medical Veterinary and Life Sciences
College of Medical Veterinary and Life Sciences > School of Cardiovascular & Metabolic Health
Journal Name:American Journal of Cardiology
ISSN:0002-9149

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