DEASON, M., Scott, R., Irwin, L., Macaulay, V. , Irving, R., Charlton, V., Morrison, E., Austin, K. and Pitsiladis, Y.P. (2012) Importance of mitochondrial haplotypes and maternal lineage in sprint performance among individuals of West African ancestry. Scandinavian Journal of Medicine and Science in Sports, 22(2), pp. 217-223. (doi: 10.1111/j.1600-0838.2010.01289.x)
Full text not currently available from Enlighten.
Abstract
Mitochondrial DNA (mtDNA) is inherited solely along the matriline, giving insight into both ancestry and prehistory. Individuals of sub-Saharan ancestry are overrepresented in sprint athletics, suggesting a genetic advantage. The purpose of this study was to compare the mtDNA haplogroup data of elite groups of Jamaican and African-American sprinters against respective controls to assess any differences in maternal lineage. The first hypervariable region of mtDNA was haplogrouped in elite Jamaican athletes (N=107) and Jamaican controls (N=293), and elite African-American athletes (N=119) and African-American controls (N=1148). Exact tests of total population differentiation were performed on total haplogroup frequencies. The frequency of non-sub-Saharan haplogroups in Jamaican athletes and Jamaican controls was similar (1.87% and 1.71%, respectively) and lower than that of African-American athletes and African-American controls (21.01% and 8.19%, respectively). There was no significant difference in total haplogroup frequencies between Jamaican athletes and Jamaican controls (P=0.551 ± 0.005); however, there was a highly significant difference between African-American athletes and African-American controls (P<0.001). The finding of statistically similar mtDNA haplogroup distributions in Jamaican athletes and Jamaican controls suggests that elite Jamaican sprinters are derived from the same source population and there is neither population stratification nor isolation for sprint performance. The significant difference between African-American sprinters and African-American controls suggests that the maternal admixture may play a role in sprint performance.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Scott, Dr Robert and Pitsiladis, Dr Yannis and Macaulay, Dr Vincent and DEASON, MICHAEL |
| Authors: | DEASON, M., Scott, R., Irwin, L., Macaulay, V., Irving, R., Charlton, V., Morrison, E., Austin, K., and Pitsiladis, Y.P. |
| College/School: | College of Science and Engineering > School of Mathematics and Statistics > Statistics |
| Journal Name: | Scandinavian Journal of Medicine and Science in Sports |
| ISSN: | 0905-7188 |
| ISSN (Online): | 1600-0838 |
| Published Online: | 16 March 2011 |
University Staff: Request a correction | Enlighten Editors: Update this record
Altmetric
Altmetric