The 2008 update of the Aspergillus nidulans genome annotation: a community effort

Wortman, J.R. et al. (2009) The 2008 update of the Aspergillus nidulans genome annotation: a community effort. Fungal Genetics and Biology, 46(1 (Sup), S2-S13. (doi: 10.1016/j.fgb.2008.12.003)

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Publisher's URL: http://dx.doi.org/10.1016/j.fgb.2008.12.003

Abstract

The identification and annotation of protein-coding genes is one of the primary goals of whole-genome sequencing projects, and the accuracy of predicting the primary protein products of gene expression is vital to the interpretation of the available data and the design of downstream functional applications. Nevertheless, the comprehensive annotation of eukaryotic genomes remains a considerable challenge. Many genomes submitted to public databases, including those of major model organisms, contain significant numbers of wrong and incomplete gene predictions. We present a community-based reannotation of the Aspergillus nidulans genome with the primary goal of increasing the number and quality of protein functional assignments through the careful review of experts in the field of fungal biology.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Clutterbuck, Dr John
Authors: Wortman, J.R., Gilsenan, J.M., Joardar, V., Deegan, J., Clutterbuck, A.J., Andersen, M.R., Archer, D., Bencina, M., Braus, G., Coutinho, P., von Döhren, H., Doonan, J., Driessen, A.J.M., Durek, P., Espeso, E., Fekete, E., Flipphi, M., Estrada, C.G., Geysens, S., Goldman, G., de Groot, P.W.J., Hansen, K., Harris, S.D., Heinekamp, T., Helmstaedt, K., Henrissat, B., Hofmann, G., Homan, T., Horio, T., Horiuchi, H., James, S., Jones, M., Karaffa, L., Karányi, Z., Kato, M., Keller, N., Kelly, D.E., Kiely, J.A.K.W., Kim, J.M., van der Klei, I.J., Klis, F.M., Kovalchuk, A., Krasevec, N., Kubicek, C.P., Liu, B., MacCabe, A., Meyer, V., Mirabito, P., Miskei, M., Mos, M., Mullins, J., Nelson, D.R., Nielsen, J., Oakley, B.R., Osmani, S.A., Pakula, T., Paszewski, A., Paulsen, I., Pilsyk, S., Pócsi, I., Punt, P.J., Ram, A.F.J., Ren, Q., Robellet, X., Robson, G., Seiboth, B., van Solingen, P., Specht, T., Sun, J., Taheri-Talesh, N., Takeshita, N., Ussery, D., vanKuyk, P.A., Visser, H., van de Vondervoort, P.J.I., de Vries, R.P., Walton, J., Xiang, X., Xiong, Y., Zeng, A.P., Brandt, B.W., Cornell, M.J., van den Hondel, C.A.M.J., Visser, J., Oliver, S.G., and Turner, G.
Subjects:Q Science > QH Natural history > QH426 Genetics
College/School:College of Medical Veterinary and Life Sciences
Journal Name:Fungal Genetics and Biology
ISSN:1087-1845
ISSN (Online):1096-0937
Published Online:25 December 2008

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