Cisplatin: polymorphism and structural insights into an important chemotherapeutic drug

Ting, V.P., Schmidtmann, M., Wilson, C.C. and Weller, M.T. (2010) Cisplatin: polymorphism and structural insights into an important chemotherapeutic drug. Angewandte Chemie (International Edition), 49(49), pp. 9408-9411. (doi: 10.1002/anie.201003185)

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Publisher's URL: http://dx.doi.org/10.1002/anie.201003185

Abstract

The changing face of cisplatin: The complete crystal structures, including the details of extensive intermolecular hydrogen bonding in two enantiotropic polymorphs of the chemotherapeutic drug cisplatin, have been elucidated. A massive thermal hysteresis effect exists between the two polymorphs, α and β, that are active at ambient temperatures.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Schmidtmann, Mr Marc and Wilson, Professor Charles
Authors: Ting, V.P., Schmidtmann, M., Wilson, C.C., and Weller, M.T.
College/School:College of Science and Engineering > School of Chemistry
Journal Name:Angewandte Chemie (International Edition)
Journal Abbr.:Angew Chem Int Ed Engl
Publisher:Wiley - V C H Verlag GmbH & Co. KGaA
ISSN:1433-7851
ISSN (Online):1521-3773
Published Online:28 October 2010

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
450251The structural chemistry of hydrogenous materialsCharles WilsonEngineering & Physical Sciences Research Council (EPSRC)EP/E050859/1Chemistry