New optical, acoustic, and electrical diagnostics for the developing world

Neale, S.L. , Witte, C., Bourquin, Y., Kremer, C., Menachery, A., Zhang, Y., Wilson, R. , Reboud, J. and Cooper, J.M. (2012) New optical, acoustic, and electrical diagnostics for the developing world. In: Microfluidics, BioMEMS, and Medical Microsystems X, San Francisco, CA, USA, 23-24 Jan 2012, p. 825102. ISBN 9780819488947 (doi:10.1117/12.924357)

Full text not currently available from Enlighten.

Abstract

Infectious diseases cause 10 million deaths each year worldwide, accounting for ~60% of all deaths of children aged 5- 14. Although these deaths arise primarily through pneumonia, TB, malaria and HIV, there are also the so called "neglected diseases" such as sleeping sickness and bilharzia, which have a devastating impact on rural communities, in sub-Sahara Africa. There, the demands for a successful Developing World diagnostic are particularly rigorous, requiring low cost instrumentation with low power consumption (there is often no fixed power infrastructure). In many cases, the levels of infection within individuals are also sufficiently low that instruments must show extraordinary sensitivity, with measurements being made in blood or saliva. In this talk, a description of these demands will be given, together with a review of some of the solutions that have been developed, which include using acoustics, optics and electrotechnologies, and their combinations to manipulate the fluid samples. In one example, we show how to find a single trypanosome, as the causative agent of sleeping sickness.

Item Type:Conference Proceedings
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Wilson, Dr Robert and Cooper, Professor Jonathan and Reboud, Dr Julien and Zhang, Mr Yi and Menachery, Dr Anoop and Neale, Dr Steven
Authors: Neale, S.L., Witte, C., Bourquin, Y., Kremer, C., Menachery, A., Zhang, Y., Wilson, R., Reboud, J., and Cooper, J.M.
College/School:College of Science and Engineering > School of Engineering > Biomedical Engineering
Journal Name:Proceedings of the SPIE: The International Society for Optical Engineering
Publisher:SPIE - The International Society for Optical Engineering
ISSN:0277-786X
ISBN:9780819488947
Published Online:09 February 2012

University Staff: Request a correction | Enlighten Editors: Update this record

Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
465001Listening to the Microworld.Jonathan CooperEngineering & Physical Sciences Research Council (EPSRC)EP/F040857/1Biomedical Engineering