Risk stratification scores in elective open abdominal aortic aneurysm repair: are they suitable for preoperative decision making?

Bryce, G.J., Payne, C.J., Gibson, S.C., Kingsmore, D.B., Byrne, D.S. and Delles, C. (2012) Risk stratification scores in elective open abdominal aortic aneurysm repair: are they suitable for preoperative decision making? European Journal of Vascular and Endovascular Surgery, 44(1), pp. 55-61. (doi: 10.1016/j.ejvs.2012.03.021)

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Abstract

Objectives<p></p> Risk indices help quantify the risk of cardiovascular events and death prior to making decisions about prophylactic AAA repair. This paper aims to study the predictive capabilities of 5 validated indices.<p></p> Design and methods<p></p> A prospective observational multi-centre cohort study from August 2005 to September 2007 in Glasgow recruited 106 consecutive patients undergoing elective open AAA repair. The Glasgow Aneurysm Score (GAS), Vascular physiology only Physiological and Operative Severity Score for enUmeration of Mortality (V(p)-POSSUM), Vascular Biochemical and Haematological Outcome Model (VBHOM), Revised Cardiac Risk Index (RCRI) and Preoperative Risk Score of the Estimation of Physiological Ability and Surgical Stress Score (PRS of E-PASS) were calculated. Indices were compared using receiver operating characteristic (ROC) analysis and area under the curve (AUC) estimates. End points were all-cause mortality, Major Adverse Cardiac Events (MACE) and cardiac death.<p></p> Results<p></p> GAS, VBHOM and RCRI did not predict outcome. V(p)-POSSUM predicted MACE (AUC = 0.681), cardiac death (AUC = 0.762) and all-cause mortality (AUC = 0.780), as did E-PASS (AUC = 0.682, 0.821, 0.703 for MACE, cardiac death and all-cause mortality respectively).<p></p> Conclusion<p></p> Whilst V(p)-POSSUM and E-PASS predicted outcome, the less complex RCRI and GAS performed poorly which questions the utility of decision making based on these surgical risk indices.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Gibson, Mr Simon and Delles, Professor Christian
Authors: Bryce, G.J., Payne, C.J., Gibson, S.C., Kingsmore, D.B., Byrne, D.S., and Delles, C.
College/School:College of Medical Veterinary and Life Sciences > Institute of Cardiovascular and Medical Sciences
College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing
Journal Name:European Journal of Vascular and Endovascular Surgery
ISSN:1078-5884
ISSN (Online):1532-2165
Published Online:21 April 2012

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