Human breast development

Gusterson, B.A. and Stein, T. (2012) Human breast development. Seminars in Cell and Developmental Biology, 23(5), pp. 567-573. (doi: 10.1016/j.semcdb.2012.03.013)

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Abstract

This review is intended to give an overview of current knowledge on human breast development. It focuses on the limitations of our understanding on the origins of human breast cancer in the context of this mainly morphological and static assessment of what is known about human breast development. The world literature is very limited and caution is needed in drawing analogies with the mouse. There is an increasing emphasis on research to understand normal stem cells in the breast on the assumption that these are the targets for the initiation of breast cancer. It is thus a priority to understand normal human breast development, but there are major obstacles to such studies mainly due to ethical considerations and to tissue acquisition.

Item Type:Articles
Keywords:Breast, development, human
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Stein, Dr Torsten and Gusterson, Professor Barry
Authors: Gusterson, B.A., and Stein, T.
Subjects:Q Science > Q Science (General)
Q Science > QM Human anatomy
R Medicine > RB Pathology
College/School:College of Medical Veterinary and Life Sciences > School of Cancer Sciences
Journal Name:Seminars in Cell and Developmental Biology
Journal Abbr.:Semin Cell Dev Biol
ISSN:1084-9521
Published Online:16 March 2012

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