Pseudohyperaldosteronism, liquorice, and hypertension

Sontia, B., Mooney, J., Gaudet, L. and Touyz, R.M. (2008) Pseudohyperaldosteronism, liquorice, and hypertension. Journal of Clinical Hypertension, 10(2), pp. 153-157. (doi: 10.1111/j.1751-7176.2008.07470.x)

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Consumption of large quantities of liquorice can cause hypokalemia and hypertension. These effects are associated with increased cortisol-mediated activation of renal mineralocorticoid receptors and hypoaldosteronism. The authors describe a patient with long-standing hypokalemia and uncontrolled hypertension related to excessive ingestion of liquorice. The case highlights the importance of obtaining a detailed dietary history, especially considering the increasing use of liquorice-containing foods, teas, and herbal products. The authors also discuss secondary causes of hypertension, focusing on pseudohyperaldosteronism.

Item Type:Articles
Glasgow Author(s) Enlighten ID:Touyz, Professor Rhian
Authors: Sontia, B., Mooney, J., Gaudet, L., and Touyz, R.M.
College/School:College of Medical Veterinary and Life Sciences > Institute of Cardiovascular and Medical Sciences
Journal Name:Journal of Clinical Hypertension
ISSN (Online):1751-7176
Published Online:14 February 2008

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