Optimization of current and future therapy for autoimmune diseases

Steinman, L., Merrill, J.T., McInnes, I.B. and Peakman, M. (2012) Optimization of current and future therapy for autoimmune diseases. Nature Medicine, 18(1), pp. 59-65. (doi:10.1038/nm.2625) (PMID:22227674)

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Publisher's URL: http://dx.doi.org/10.1038/nm.2625


There are multiple immune-based therapeutics available for some of the most prevalent autoimmune diseases, but for others, there are few or no approved immune therapies. This dichotomy poses discrete challenges. First, for diseases in which multiple therapy choices exist, a rational decision tree is required to select the best therapy. Second, we must devise new strategies for the autoimmune diseases that have the highest unmet clinical need. This commentary outlines new strategies for designing more efficient and selective approaches for immune therapy of autoimmune diseases.

Item Type:Articles
Glasgow Author(s) Enlighten ID:McInnes, Professor Iain
Authors: Steinman, L., Merrill, J.T., McInnes, I.B., and Peakman, M.
College/School:College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation
Journal Name:Nature Medicine
ISSN (Online):1546-170X
Published Online:06 January 2012

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