Nebulisation on a disposable array structured with phononic lattices

Reboud, J. , Wilson, R. , Zhang, Y., Ismail, M. H., Bourquin, Y. and Cooper, J. M. (2012) Nebulisation on a disposable array structured with phononic lattices. Lab on a Chip, 12(7), pp. 1268-1273. (doi:10.1039/C2LC20705B)

Reboud, J. , Wilson, R. , Zhang, Y., Ismail, M. H., Bourquin, Y. and Cooper, J. M. (2012) Nebulisation on a disposable array structured with phononic lattices. Lab on a Chip, 12(7), pp. 1268-1273. (doi:10.1039/C2LC20705B)

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Publisher's URL: http://dx.doi.org/10.1039/C2LC20705B

Abstract

We demonstrate the use of a phononic crystal to enable the nebulisation of liquid droplets from low-cost disposable arrays, using surface acoustic waves (SAW). The SAWs were generated using interdigitated transducers (IDT) on a piezoelectric surface (LiNbO3) and the acoustic waves were coupled into a disposable phononic crystal structure, referred to as a superstrate. Using its excellent reflecting properties, the phononic structures confined the acoustic field within the superstrate, resulting in the concentration of the acoustic energy, in a manner controllable by the excitation frequency. We show that this capability mitigates against coupling losses incurred by the use of a disposable superstrate, greatly reducing the time needed to nebulise a drop of water with respect to an unstructured superstrate for a given power. We also demonstrate that by changing the excitation frequency, it is possible to change the spatial position at which the acoustic energy is concentrated, providing a means to specifically nebulise drops across an array. These results open up a promising future for the use of phonofluidics in high-throughput sample handling applications, such as drug delivery or the “soft” transfer of samples to a mass spectrometer in the field of proteomics.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Wilson, Dr Robert and Zhang, Mr Yi and Cooper, Professor Jonathan and Reboud, Dr Julien
Authors: Reboud, J., Wilson, R., Zhang, Y., Ismail, M. H., Bourquin, Y., and Cooper, J. M.
College/School:College of Science and Engineering > School of Engineering > Biomedical Engineering
Journal Name:Lab on a Chip
Publisher:Royal Society of Chemistry
ISSN:1473-0197
ISSN (Online):1473-0189
Published Online:10 February 2012

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
465001Listening to the Microworld.Jonathan CooperEngineering & Physical Sciences Research Council (EPSRC)EP/F040857/1Biomedical Engineering
553521Next Generation Analytical Tools: Application to Protein Oxidations that affect Human Health and WellbeingJonathan CooperEngineering & Physical Sciences Research Council (EPSRC)EP/I017887/1ENG - BIOMEDICAL ENGINEERING