Enlighten
Research publications by members of the University of Glasgow
home > services > Enlighten

Comparison of solid phase extraction and supercritical fluid extraction for the analysis of morphine in whole blood

Allen, D.L., Scott, K.S., and Oliver, J.S. (1999) Comparison of solid phase extraction and supercritical fluid extraction for the analysis of morphine in whole blood. Journal of Analytical Toxicology, 23 . pp. 216-218. ISSN 0146-4760

Full text not currently available from Enlighten.

Abstract

A comparative study of the quantitative determination of morphine in whole blood using solid-phase extraction (SPE) and supercritical fluid extraction (SFE) is described. Comparative studies were made of the two techniques for the extraction of morphine from authentic forensic blood specimens. Quantitative results indicate that morphine levels measured using SPE correspond well to morphine levels produced using SFE. The two techniques are therefore comparable, although SFE is faster and cleaner and extracts may be produced with higher analyte recoveries than with SPE. This paper presents a comparison of the two techniques and the morphine concentrations determined in blood.

Item Type:Article
Status:Published
Refereed:Yes
Glasgow Author(s):Scott, Dr Karen
Authors: Allen, D.L., Scott, K.S., and Oliver, J.S.
College/School:College of Medical Veterinary and Life Sciences > School of Medicine > Clinical Specialities
Journal Name:Journal of Analytical Toxicology
ISSN:0146-4760

University Staff: Request a correction | Enlighten Editors: Update this record