Day, P.F., Gregg, T.A., Ashley, P., Welbury, R.R., Cole, B.O., High, A.S. and Duggal, M.S. (2012) Periodontal healing following avulsion and replantation of teeth: a multi-centre randomized controlled trial to compare two root canal medicaments. Dental Traumatology, 28(1), pp. 55-64. (doi: 10.1111/j.1600-9657.2011.01053.x)
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Abstract
Background: Non-setting calcium hydroxide (Ultracal XS®) is recommended by the International Association of Dental Traumatology as the initial medicament following avulsion and replantation for mature teeth. There is experimental evidence to suggest Ledermix®, placed as an alternative inter-visit dressing may improve periodontal healing. Aim: This study investigated, using a multi-centre randomized controlled trial, the effect of two root canal medicaments, Ledermix® and Ultracal XS®, on periodontal healing of avulsed and replanted teeth. Material and methods: Children were recruited if they fulfilled all inclusion criteria. Treatment followed a standardized protocol. Assessment of periodontal healing or ankylosis was made clinically and radiographically by an experienced, ‘blinded’, clinician at 12 months. Results: Over 200 patients were assessed for eligibility at five centres. Twenty-nine patients were eligible for inclusion. Final analysis involved 22 patients with 27 teeth. Ankylosis was detected in four of the 12 teeth in the Ledermix® group and nine of 15 in the Ultracal XS® group. No significant difference between medicaments was found in the proportion of teeth or patients showing periodontal healing. Discussion: There was no significant difference in periodontal healing between the two medicaments at either a tooth or patient level. The numbers recruited fell short of an estimated power calculation. For patients meeting the inclusion criteria and completing the trial, periodontal healing was seen in 52% of teeth at the 12-month assessment between both groups. The only factor found to significantly influence the periodontal outcome was dry time.
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Welbury, Professor Richard |
Authors: | Day, P.F., Gregg, T.A., Ashley, P., Welbury, R.R., Cole, B.O., High, A.S., and Duggal, M.S. |
College/School: | College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing > Dental School |
Journal Name: | Dental Traumatology |
ISSN: | 1600-4469 |
Published Online: | 11 October 2011 |
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