Anti-Mullerian hormone: clairvoyance or crystal clear?

Nelson, S.M. , Anderson, R.A., Broekmans, F.J., Raine-Fenning, N., Fleming, R. and La Marca, A. (2012) Anti-Mullerian hormone: clairvoyance or crystal clear? Human Reproduction, 27(3), pp. 631-636. (doi:10.1093/humrep/der446)

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Abstract

The clinical use of anti-Müllerian hormone (AMH) has increased exponentially due to its unique relationship with the ovarian reserve and ability to predict ovarian response, facilitate pretreatment counselling and individualize treatment strategies to minimize the risk of ovarian hyperstimulation syndrome. There is now a rapidly increasing literature examining additional possibilities for AMH, all of which suggest that its reach extends far beyond the assisted conception clinic. The recognition that it is a significantly more accurate and reliable measure of ovarian reserve than the antral follicle count or FSH has led to its adoption by physicians to counsel women on their reproductive lifespan, the impact of gonadotoxic chemotherapy, radiotherapy and surgery on the ovarian reserve and allow polycystic ovarian syndrome to be diagnosed by primary care physicians. We propose that there is an adequate literature base to embrace this technology while continuing to develop and refine how AMH can optimize patient care.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Nelson, Professor Scott and Fleming, Professor Richard
Authors: Nelson, S.M., Anderson, R.A., Broekmans, F.J., Raine-Fenning, N., Fleming, R., and La Marca, A.
College/School:College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing
Journal Name:Human Reproduction
ISSN:0268-1161
ISSN (Online):1460-2350
Published Online:11 January 2012

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