Evidence for the localization of the Arabidopsis cytokinin receptors AHK3 and AHK4 in the endoplasmic reticulum

Caesar, K., Thamm, A.M.K., Witthoft, J., Elgass, K., Huppenberger, P., Grefen, C., Horak, J. and Harter, K. (2011) Evidence for the localization of the Arabidopsis cytokinin receptors AHK3 and AHK4 in the endoplasmic reticulum. Journal of Experimental Botany, 62(15), pp. 5571-5580. (doi: 10.1093/jxb/err238)

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Publisher's URL: http://dx.doi.org/10.1093/jxb/err238

Abstract

Cytokinins are hormones that are involved in various processes of plant growth and development. The model of cytokinin signalling starts with hormone perception through membrane-localized histidine kinase receptors. Although the biochemical properties and functions of these receptors have been extensively studied, there is no solid proof of their subcellular localization. Here, cell biological and biochemical evidence for the localization of functional fluorophor-tagged fusions of <i>Arabidopsis</i> histidine kinase 3 (AHK3) and 4 (AHK4), members of the cytokinin receptor family, in the endoplasmic reticulum (ER) is provided. Furthermore, membrane-bound AHK3 interacts with AHK4 in vivo. The ER localization and putative function of cytokinin receptors from the ER have major impacts on the concept of cytokinin perception and signalling, and hormonal cross-talk in plants

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Grefen, Dr Christopher
Authors: Caesar, K., Thamm, A.M.K., Witthoft, J., Elgass, K., Huppenberger, P., Grefen, C., Horak, J., and Harter, K.
College/School:College of Medical Veterinary and Life Sciences > Institute of Molecular Cell and Systems Biology
Journal Name:Journal of Experimental Botany
ISSN:0022-0957
ISSN (Online):1460-2431
Published Online:12 August 2011

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