Body weight in early and mid-adulthood in relation to subsequent coronary heart disease mortality: 80-year follow-up in the Harvard Alumni Study

Gray, L. , Lee, I.-M., Sesso, H.D. and Batty, G.D. (2011) Body weight in early and mid-adulthood in relation to subsequent coronary heart disease mortality: 80-year follow-up in the Harvard Alumni Study. Archives of Internal Medicine, 171(19), pp. 1768-1770. (doi: 10.1001/archinternmed.2011.486)

Abstract

In the very few studies conducted,obesity in young adults is generally associated with an increased risk of future coronary heart disease (CHD). However, data interpretation is complicated by methodological limitations, which include small study size; a paucity of studies examining the impact of confounding factors; and unexplored mechanisms, including the essentially unknown contributions of early vs later body weight on CHD risk,5-6 which has implications for weight control interventions. In the largest and best characterized study to date, to our knowledge, we directly address these shortcoming.

• Item Type: Articles
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Gray, Dr Linsay and Batty, Dr G
• Authors: Gray, L., Lee, I.-M., Sesso, H.D., and Batty, G.D.
• College/School: College of Medical Veterinary and Life Sciences > School of Health & Wellbeing > MRC/CSO SPHSU; College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing
• Journal Name: Archives of Internal Medicine
• ISSN: 0003-9926
• ISSN (Online): 2168-6114